Table 5 Examination of differential early and late effects in risk of all-cause mortality according to post diagnosis use of aspirin or NSAIDs
Patient status at end of follow-up | Multivariate a | |||||
|---|---|---|---|---|---|---|
Drug type | Period examined | Post diagnosis exposure | Alive | Dead | HR | (95% CI) |
Aspirin | 0–5 years | Unexposed | 3885 | 3498 | 1 | |
Exposed | 1143 | 776 | 0.83 | (0.75, 0.92) | ||
5–10 years | Unexposed | 2160 | 708 | 1 | ||
Exposed | 440 | 156 | 1.28 | (1.05, 1.54) | ||
>10 years | Unexposed | 880 | 194 | 1 | ||
Exposed | 78 | 26 | 1.95 | (1.27, 2.99) | ||
NSAIDs | 0–5 years | Unexposed | 4625 | 3780 | 1 | |
Exposed | 403 | 494 | 1.34 | (1.21, 1.49) | ||
5–10 years | Unexposed | 2351 | 797 | 1 | ||
Exposed | 249 | 67 | 0.99 | (0.77, 1.28) | ||
>10 years | Unexposed | 886 | 196 | 1 | ||
Exposed | 72 | 24 | 1.57 | (1.01, 2.42) | ||
