Table 1 Hormone values and sperm counts according to treatment groupa

From: Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer

 

Surgery ( n =232)

RT ( n =485)

Cis=850 mg ( n =381)

Cis>850 mg ( n =93)

Total ( n =1191)

P- value

s-FSH, geometric mean (range), IU l−1

9.6 (2.8–60.9)

10.3 (1.9–86.5)

11.5 (0.5–64.4)

16.9 (1.3–66.3)

10.9 (0.5–86.5)

<0.001b

s-Inhibin B, median (range), ng l−1

70 (<7–203)

62 (<7–256)

41 (<7–271)

<7 (<7–211)

57 (<7–271)

<0.001c

Sperm count, median (range), millions per ml

30 (0–293)

24 (0–283)

18 (0–480)

1 (0–98)

24 (0–480)

0.001c

  1. Abbreviations: ANOVA=analysis of variance; Cis=cisplatin; FSH=follicle stimulating hormone; s=serum; RT=radiotherapy.
  2. as-Inhibin B available in 441 cases. Sperm counts available in 342 cases.
  3. bOne-way ANOVA (performed on the log-transformed value due to skewness).
  4. cKruskal–Wallis test.
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