Table 2 Variations in s-FSH (%) and s-inhibin B (absolute values) with 95% CI according to age, follow-up time, treatment group, and cryptorchism

From: Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer

 

s-FSH

s-Inhibin B

 

Increase (%) a

95% CI

P- value

Regression co-efficient b

95% CI

P- value

Age (10-year interval)

22

16, 27

<0.001

−15

−21, −8

<0.001

Follow-up time (10-year interval)

−1

−10, 9

0.9

5

−10, 19

0.5

Treatment

<0.001

  

<0.001

 Surgery

Reference

  

Reference

  

 RT

−0.01

−10, 10

0.9

2

−12, 16

0.8

 Cis850 mg

21

9, 34

<0.001

−19

−36, −2

0.031

 Cis>850 mg

89

61, 121

<0.001

−61

−90, −32

<0.001

Cryptorchism

<0.001

  

0.6

 No

Reference

  

Reference

  

 Yes

24

11, 37

 

−5

−22, 12

 
  1. Abbreviations: CI=confidence interval; Cis=cisplatin; FSH=follicle stimulating hormone; RT=radiotherapy.
  2. aOn the basis of linear regression analyses, the analysis was performed on the logarithmic value of s-FSH; numbers stated as % are the exponentially transformed regression co-efficients.
  3. bOn the basis of tobit censored linear regression, the regression co-efficient corresponds to change in absolute values of s-inhibin B (ng l−1).