Table 1 Comparison of mutation spectrum in control, bystander and irradiated lung tissues at 24 h after PBIR

From: Radiation induced COX-2 expression and mutagenesis at non-targeted lung tissues of gpt delta transgenic mice

   

Larger deletion (>2 kb)

Smaller deletion (<2 kb)+site mutation

 

MF (10−6)

Total no. of clones

No.

%

MF (10−6)

No.

%

MF (10−6)

Control

2.86

23

3

13

0.37

20

87

2.49

1 day post-PBIR 5 Gy

6.91

88

62

70

4.84

26

30

2.07

1 day post-WBIR 5 Gy

8.52

30

6

20

1.70

24

80

6.82

  1. Abbreviations: MF=mutation frequency; PBIR=partial body irradiation; WBIR=whole-body irradiation.
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