Figure 1

Immunostaining of REG I α in biopsy samples obtained from gastric cancer tissues. The biopsy samples were obtained before chemotherapy (A, B, and D) and after disease progression (C). (A) The REG Iα-negative gastric cancer (diffuse type). (B) The REG Iα-positive gastric cancer (intestinal type). (C) The REG Iα-positive gastric cancer (diffuse type). This sample was obtained from the same patient as that in (A) when he developed disease progression after S-1/CDDP treatment. (D) The REG Iα-positive signet-ring cell carcinoma (diffuse type).