Figure 6
From: The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis

Comparison of the effect of lovastatin in HGT-1 and HGT-1-D5 cells. HGT-1 and HGT-1-D5 cells were treated with 0, 2.5, or 5 μ M lovastatin for 48 or 72 h (A). Apoptosis was determined by Hoechst 33342 staining. Values are means±s.d (n=3). *P<0.1 or **P<0.01 for HGT-1-D5 cells compared with HGT-1 cells (Student's t-test). (B) HGT-1 and HGT-1-D5 cells were treated with 2.5 μ M lovastatin for 72 h. Protein levels were analysed by western blotting. Hsc70 was used as a loading control. The western blotting analyses are representative of three experiments with similar results.