Table 3 Hazard ratios (HRs) for death and their 95% confidence intervals (CIs) according to partner's vital status and time between diagnosis, death and death of partner among 21 213 women with breast cancer diagnosed in 1994–2006, Denmark

From: Loss of partner and breast cancer prognosis — a population-based study, Denmark, 1994–2010

    

Crude a

Adjusted HR b

Adjusted HR c

 

N

Person years

Events

HR d

(95% CI)

HR d

(95% CI)

HR d

(95% CI)

All-cause mortality

 Exposure before diagnosis

Time from bereavement to diagnosis (years)

 [0–1]

228

1610

76

1.17

(0.93, 1.48)

1.15

(0.91, 1.44)

1.04

(0.82, 1.34)

 ]1–2]

195

1391

65

1.14

(0.89, 1.46)

1.04

(0.81, 1.34)

1.05

(0.80, 1.38)

 ]2–4]

339

2215

102

1.11

(0.91, 1.36)

1.04

(0.85, 1.26)

1.19

(0.96, 1.47)

 Exposure after diagnosis

Time from bereavement to death (years)

 [0–1]

647

5768

173

1.20

(0.98, 1.48)

1.16

(0.95, 1.43)

1.11

(0.89, 1.39)

 [1–5]

766

7237

156

1.11

(0.97, 1.28)

1.08

(0.94, 1.23)

1.09

(0.94, 1.26)

 >5

846

10142

111

1.07

(0.88, 1.31)

1.04

(0.85, 1.27)

1.08

(0.87, 1.34)

Recurrence

 Exposure before diagnosis

Time from bereavement to diagnosis (years)

 [0–1]

228

904

15

0.66

(0.40, 1.10)

0.66

(0.39, 1.09)

0.57

(0.32, 1.01)

 [1–2]

195

800

14

0.71

(0.42, 1.20)

0.69

(0.41, 1.17)

0.74

(0.42, 1.32)

 [2–4]

339

1135

30

1.05

(0.73, 1.51)

1.03

(0.72, 1.49)

1.11

(0.74, 1.65)

 Exposure after diagnosis

Time from bereavement to death (years)

 [0–1]

467

2439

48

0.90

(0.61, 1.34)

0.90

(0.60, 1.33)

0.73

(0.46, 1.17)

 [1–5]

412

2837

28

1.01

(0.76, 1.34)

1.00

(0.75, 1.33)

1.01

(0.75, 1.36)

 >5

260

2306

9

1.02

(0.52, 2.00)

1.02

(0.52, 2.00)

1.16

(0.57, 2.37)

  1. aStratified by age at diagnosis in 1-year intervals.
  2. bAdjusted for the highest-attained educational level, disposable income and stratified by age at diagnosis in 1-year intervals.
  3. cAdjusted for the highest-attained educational level, disposable income, period of diagnosis, comorbidity, tumour size, no. of tumour-positive lymph-nodes, hormone receptor status, malignancy grade and stratified by age at diagnosis in 1-year intervals (N=19 186) (defined in Table 1).
  4. dThe reference category (HR=1) are not experiencing the death of a cohabiting partner in the given year-interval.