Figure 6
DMS 79 xenograft tumours retain their neuroendocrine phenotype in vivo and show local invasion into the capsule. DMS 79 tumours were excised at 1000 mm3 and whole sections stained for POMC (A), cytokeratin (B), NSE (C) and vimentin (D). POMC DAB staining revealed tumour cells that had invaded into the surrounding capsule/muscle tissue (E–G). Red arrows indicate tumour cells that have invaded into the capsule through muscle layers, or are actively invading through muscle. m=myocytes, c=fibrotic capsule, f=fat deposits.
