Table 5 Sensitivity analyses of the association between childhood acute leukaemia and distance to the closest HVOL by category of voltage (very high (225–400 kV) or high (63–150 kV)) over the period 2002–2007, for all ages and the 0–4-years age group

From: Childhood leukaemia close to high-voltage power lines – the Geocap study, 2002–2007

 

Main results

Sensitivity analyses

 

GIS with any uncertainty

(1) GIS with uncertainty of 20 m

(2) Photographic views available

   

Photograph only

<50 m by GIS or photo

<50 m by GIS and photo

 

Ca

Co

OR

95% CI

Ca

Co

OR

95% CI

Ca

Co

OR

95% CI

Ca

Co

OR

95% CI

Ca

Co

OR

95% CI

0–14 years

Baseline

610

7061

1.0

Reference

610

7061

1.0

Reference

610

7061

1.0

Reference

610

7061

1.0

Reference

610

7061

1.0

Reference

Any HVOL

 100–199 m

44

669

0.8

(0.5–1.0)

32

499

0.7

(0.5–1.1)

36

455

0.9

(0.6–1.3)

        

 50–99 m

25

284

1.0

(0.7–1.6)

20

212

1.1

(0.7–1.8)

22

184

1.4

(0.9–2.2)

        

 0–49 m

23

213

1.2

(0.8–1.9)

16

152

1.2

(0.7–2.0)

14

158

1.1

(0.6–1.9)

24

243

1.2

(0.7–1.8)

13

128

1.2

(0.7–2.1)

VHV-HVOL

 100–199 m

16

267

0.7

(0.4–1.2)

13

200

0.8

(0.4–1.3)

18

172

1.2

(0.7–1.9)

        

 50–99 m

8

97

1.0

(0.5–2.1)

6

68

1.0

(0.4–2.4)

8

74

1.3

(0.6–2.7)

        

 0–49 m

9

60

1.7

(0.9–3.6)

7

39

2.1

(0.9–4.7)

4

38

1.3

(0.5–3.7)

9

68

1.5

(0.8–3.1)

4

30

1.7

(0.6–4.8)

HV-HVOL

 100–199 m

33

461

0.8

(0.6–1.2)

22

346

0.7

(0.5–1.1)

24

322

0.9

(0.6–1.3)

        

 50–99 m

21

203

1.2

(0.7–1.9)

16

155

1.2

(0.7–2.0)

14

121

1.3

(0.7–2.3)

        

 0–49 m

14

164

1.0

(0.6–1.7)

9

120

0.8

(0.4–1.7)

10

127

0.9

(0.5–1.8)

15

188

0.9

(0.5–1.6)

9

103

1.0

(0.5–2.0)

0–4 years

Baseline

311

2326

1.0

Reference

311

2326

1.0

Reference

311

2326

1.0

Reference

311

2326

1.0

Reference

311

2326

1.0

Reference

Any HVOL

 100–199 m

17

213

0.6

(0.3–1.0)

9

160

0.4

(0.2–0.8)

16

146

0.9

(0.5–1.5)

        

 50–99 m

14

84

1.2

(0.7–2.1)

11

62

1.2

(0.6–2.4)

13

55

1.7

(0.9–3.3)

        

 0–49 m

14

62

1.5

(0.8–2.8)

9

42

1.3

(0.6–2.8)

8

38

1.5

(0.6–3.3)

14

66

1.4

(0.8–2.6)

8

34

1.7

(0.8–3.9)

VHV-HVOL

 100–199 m

5

87

0.4

(0.2–1.0)

4

63

0.5

(0.2–0.4)

9

58

1.3

(0.6–2.8)

        

 50–99 m

6

27

1.6

(0.7–4.1)

4

19

1.6

(0.5–5.0)

6

21

2.1

(0.8–5.8)

        

 0–49 m

6

14

2.6

(1.0–6.9)

5

8

4.1

(1.3–13.3)

3

7

2.5

(0.6–10.5)

6

16

2.3

(0.9–6.0)

3

5

3.5

(0.8–15.1)

HV-HVOL

 100–199 m

13

108

0.6

(0.4–1.2)

6

145

0.4

(0.2–0.9)

10

99

0.7

(0.4–1.4)

        

 50–99 m

11

45

1.3

(0.7–2.5)

8

61

1.2

(0.5–2.6)

7

35

1.5

(0.6–3.4)

        

 0–49 m

8

36

1.1

(0.5–2.3)

4

52

0.6

(0.2–1.8)

5

33

1.1

(0.4–2.9)

8

55

1.0

(0.5–2.1)

5

30

1.3

(0.5–3.4)

  1. Abbreviations: Ca=number of cases; CI=confidence interval; Co=number of controls; GIS=geographic information system; HV-HVOL=high voltage high-voltage overhead power lines (63-150 kV); HVOL=high-voltage overhead power line; OR=odds ratio; VHV-HVOL=very high voltage high-voltage overhead power lines (225-400 kV).
  2. The first sensitivity analysis (1) is restricted to the addresses best geocoded (GIS obtained with uncertainty of 20 m) and the second one (2) to the addresses for which a photographic view was available. The results shown in Tables 4 and 5 are recalled in the first columns.
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