Table 3 One-, five- and ten-year survival rates and unadjusted hazard ratios and 95% confidence intervals by demographic and clinical predictor factors for acute lymphoblastic leukaemia cases only (N=144)
From: Socioeconomic variation in survival from childhood leukaemia in northern England, 1968–2010
Variable | One-year survival (% (95% CI)) | Five-year survival (% (95% CI)) | Ten-year survival (%) | Hazard ratio (95% CI) | P -value |
|---|---|---|---|---|---|
Sex | |||||
Female | 55 (43–66) | 44 (31–56) | 44 (31–56) | 1.00 | |
Male | 54 (43–65) | 41 (30–52) | 41 (30–52) | 1.10 (0.71–1.70) | 0.67 |
Age group (years) | |||||
0–1 | 57 (39–72) | 49 (31–64) | 49 (31–64) | 1.00 | |
2–4 | 61 (40–76) | 50 (30–66) | 50 (30–66) | 0.94 (0.47–1.88) | 0.86 |
5–9 | 58 (41–72) | 39 (24–54) | 39 (24–54) | 1.20 (0.65–2.22) | 0.55 |
10–14 | 46 (31–60) | 35 (21–50) | 35 (21–50) | 1.31 (0.72–2.38) | 0.39 |
Calendar period | |||||
1968–1977 | 20 (10–33) | 2 (0–10) | 2 (0–10) | 1.00 | |
1978–1987 | 21 (9–38) | 14 (5–30) | 14 (5–30) | 0.65 (0.40–1.08) | 0.098 |
1988–1997 | 91 (69–98) | 83 (60–93) | 83 (60–93) | 0.07 (0.03–0.19) | <0.0001 |
1997–2010 | 91 (78–97) | 80 (64–89) | 80 (64–89) | 0.07 (0.03–0.15) | <0.0001 |
Paternal social class | |||||
I/II | 67 (34–86) | 58 (27–80) | 58 (27–80) | 1.00 | 0.26 |
IIIN/M | 56 (41–68) | 41 (28–55) | 41 (28–55) | 1.47 (0.57–3.80) | 0.43 |
IV/V | 42 (25–58) | 32 (17–49) | 32 (17–49) | 2.05 (0.77–5.44) | 0.15 |
White blood cell count | |||||
0–50 000 | No observation | 92 (57–99) | 92 (57–99) | 1.00 | |
>50 000 | 60 (46–71) | 48 (36–60) | 48 (36–60) | 9.44 (1.29–69.11) | 0.03 |
