Table 2 Diabetes in relation to hepatocellular carcinoma (HCC) in total subjects, males and females separately, and by duration of diabetes prior to baseline interivew, Singapore Chinese Health Study 1993–2010

From: Diabetes mellitus and risk of hepatocellular carcinoma: findings from the Singapore Chinese Health Study

 

Total number N (%)

HCC cases

HR (95% CI) a

HR (95% CI) b

All

Non-diabetics

55 852 (91.1)

412

1.00

1.00

Diabetics

5469 (8.9)

87

2.64 (2.09–3.33)

2.14 (1.69–2.71)

Men

Non-diabetics

24 933 (91.4)

303

1.00

1.00

Diabetics

2360 (8.6)

58

2.51 (1.89–3.32)

2.11 (1.58–2.81)

Women

Non-diabetics

30 919 (90.9)

109

1.00

1.00

Diabetics

3109 (9.1)

29

3.27 (2.17–4.92)

2.14 (1.41–3.25)

Number of years of diabetes diagnosed prior to baseline interview

Non-diabetics

55 852 (91.1)

412

1.00

1.00

<5 years

2139 (3.5)

39

2.80 (2.01–3.89)

2.41 (1.73–3.35)

5–10 years

1341 (2.2)

21

2.53 (1.63–3.92)

2.14 (1.38–3.33)

10 years

1989 (3.2)

27

2.52 (1.7–3.71)

1.84 (1.24–2.72)

  1. aCrude hazard ratio.
  2. bAdjusted for age, year of recruitment, gender, dialect group, level of education, cigarette smoking status, alcohol intake frequency, body mass index, and consumption of coffee and tea; HR, hazard ratio; CI, confidence interval.