Table 2 Cox proportional regression analysis for the prediction of the PCa patients’ DFS

From: The loss of the tumour-suppressor miR-145 results in the shorter disease-free survival of prostate cancer patients

 

Univariate analysis

Multivariate analysis

Covariant

HR

95% CI a

P -value b

HR

95% CI a

P -value b

miR-145

Positive

1.00

  

1.00

  

Negative

2.533

1.249–5.137

0.010

1.264

0.489–3.273

0.629

Gleason score

2.244

1.407–3.578

0.001

1.660

0.944–2.921

0.078

Clinical stage

1.504

1.178–1.922

0.001

1.151

0.818–1.621

0.419

PSA

1.092

1.035–1.151

0.001

1.034

0.957–1.117

0.397

Age

0.996

0.944–1.051

0.877

0.983

0.930–1.039

0.548

DRE

2.285

1.104–4.727

0.026

1.535

0.679–3.469

0.303

  1. Abbreviations: CI=confidence interval; DFS=disease-free survival; DRE=digital rectal examination; HR=hazard ratio; PCa=prostate cancer.
  2. aCI of the estimated HR.
  3. Test for trend.
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