Table 1 Clinical, mammographic and histopathological characteristics of all study subjects. Numbers in each subset vary depending on availability of slides and mammograms
Subcohort | Cases outside subcohort | |||
|---|---|---|---|---|
Age, mean (s.d.) | 56.7 | (9.2) | 55.4 | (9.4) |
Randomized to, No. (%) | ||||
RT | 148 | (51.6) | 44 | (29.1) |
Control | 139 | (48.4) | 107 | (70.9) |
Detection mode, No. (%) | ||||
Screening detected | 220 | (76.9) | 108 | (71.5) |
Not screening detected | 66 | (23.1) | 43 | (28.5) |
Palpation, No. (%) | ||||
Palpable | 73 | (25.4) | 38 | (25.2) |
Not palpable | 208 | (72.5) | 109 | (72.2) |
Unknown | 6 | (2.1) | 4 | (2.6) |
Tumour size, No. (%) | ||||
<10 | 64 | (22.3) | 23 | (15.2) |
10–19 | 111 | (38.7) | 42 | (27.8) |
20–39 | 70 | (24.4) | 43 | (28.5) |
40+ | 18 | (6.3) | 16 | (10.6) |
Missing data | 24 | (8.4) | 27 | (17.9) |
Surgical margins, No. (%) | ||||
Pathological margins clear | 199 | (81.6) | 86 | (70.5) |
Pathological margins positive | 26 | (10.7) | 25 | (20.5) |
Pathological margins unknown or missing | 19 | (7.8) | 11 | (9.0) |
Mammographic pattern, No. (%) | ||||
No calcifications | 32 | (13.1) | 9 | (7.4) |
Architectural distortion/galactography | 22 | (9.0) | 8 | (6.6) |
Powdery | 25 | (10.2) | 7 | (5.7) |
Crushed stone-like | 126 | (51.6) | 68 | (55.7) |
Casting-type | 39 | (16.0) | 30 | (24.6) |
Cancer type a , No. (%) | ||||
Paget/microinvasive/invasive | 11 | (3.8) | 12 | (9.9) |
Benign/ADH/LCIS | 24 | (8.4) | 3 | (2.5) |
Missing/bad material | 22 | (7.7) | 8 | (6.6) |
DCIS | 229 | (80.1) | 98 | (81.0) |
Necrosis among DCIS-patients b , No. (%) | ||||
Necrosis | 169 | (73.8) | 85 | (86.7) |
No necrosis | 60 | (26.2) | 13 | (13.3) |
Nuclear grade among DCIS patients b , No. (%) | ||||
NG=1 | 20 | (8.7) | 3 | (3.1) |
NG=2 | 95 | (41.5) | 32 | (32.7) |
NG=3 | 114 | (49.8) | 63 | (64.3) |