Figure 1

Scatter plots of log RR estimates from published population-based studies ( Supplementary Table 1 ) (all x -axes) vs: (A) logistic regression estimates comparing AOCS controls against all familial cases (Table 2); (B) logistic regression estimates comparing AOCS controls against one selected female case per family (Table 2); (C) single gene segregation model estimates (Table 3); and (D) polygenic segregation model estimates (Table 3). The dashed line is y=x, the line of equality. ICC=intraclass correlation coefficient.