Table 1 Comparison of patient, tumour, and treatment characteristics among the four broad ethnic groups of women aged 18–39 years with breast cancer

From: Comparison of clinicopathologic features and survival in young American women aged 18–39 years in different ethnic groups with breast cancer

Characteristic

Non-Hispanic white ( n =35 101)

Black ( n =8215)

Hispanic white ( n =7067)

Asian ( n =4770)

P- value

Disease stage

    

<0.0001a

Localised

17 602 (51.6)

3538 (44.3)

3035 (44.3)

2477 (52.9)

 

Regional

14 936 (43.8)

3785 (47.4)

3356 (48.9)

1978 (42.3)

 

Distant

1581 (4.6)

659 (8.3)

465 (6.8)

225 (4.8)

 

Unknown

982

233

211

90

 

Age at diagnosis (years)

    

0.0001b

Mean (median)

35 (36)

34.4 (35)

34.5 (35)

35 (36)

 

<35 years

12 421 (35.4)

3499 (42.6)

2930 (41.5)

1718 (36.0)

<0.0001

35 years

22 680 (64.6)

4716 (57.4)

4137 (58.5)

3052 (64.0)

 

Surgery

    

<0.0001a

No primary surgery

1030 (3.0)

583 (7.2)

477 (6.8)

175 (3.7)

 

SM

11 835 (34.2)

2929 (36.2)

2584 (36.9)

1775 (37.5)

 

TM

21 731 (62.8)

4584 (56.6)

3948 (56.3)

2780 (58.8)

 

Unknown

505

119

58

40

 

Tumour grade

    

<0.0001a

I

1816 (7.3)

278 (4.6)

336 (5.7)

336 (8.8)

 

II

7905 (31.8)

1521(24.9)

1744 (29.5)

1338 (35.0)

 

III

14 045 (56.4)

4079 (66.8)

3553 (60.1)

2018 (52.7)

 

IV

1119 (4.5)

225 (3.7)

276 (4.7)

135 (3.5)

 

Unknown

10216

2112

1158

943

 

Histology

    

<0.0001

IDC

26 973 (76.8)

6227 (75.8)

5441 (77.0)

3793 (79.5)

 

ILC

1170 (3.3)

194 (2.4)

186 (2.6)

97 (2.0)

 

IDC and ILC

1522 (4.3)

231 (2.8)

337 (4.8)

194 (4.1)

 

Other

5436 (15.5)

1563 (19.0)

1103 (15.6)

686 (14.4)

 

Oestrogen receptor status

    

<0.0001a

Positive

13 362 (62.0)

2667 (49.9)

3035 (57.8)

2379 (67.8)

 

Negative

8010 (37.2)

2636 (49.3)

2185 (41.7)

1115 (31.7)

 

Borderline

172 (0.8)

42 (0.8)

26 (0.5)

17 (0.5)

 

Unknown

13 557

2870

1821

1259

 

Progesterone receptor status

    

<0.0001a

Positive

11 995 (56.3)

2280 (43.2)

2606 (50.5)

2180 (63.1)

 

Negative

9117 (42.8)

2941 (55.8)

2514 (48.7)

1241 (35.9)

 

Borderline

198 (0.9)

51 (1.0)

41 (0.8)

35 (1.0)

 

Unknown

13 791

2943

1906

1314

 

Adjuvant radiation therapy

    

<0.0001

No

21 357 (60.8)

5105 (62.1)

4206 (59.5)

2722 (57.1)

 

Yes

13 744 (39.2)

3110 (37.9)

2861 (40.5)

2048 (42.9)

 

Adjuvant radiation therapy after SM

    

<0.0001

No

3576 (30.2)

1107 (37.8)

971 (37.6)

532 (30.0)

 

Yes

8259 (69.8)

1822 (62.2)

1613 (62.4)

1243 (70.0)

 

Adjuvant radiation therapy after TM

    

<0.0001

No

16 318 (75.1)

3331 (72.7)

2721 (68.9)

1984 (71.4)

 

Yes

5413 (24.9)

1253 (27.3)

1227 (31.1)

796 (28.6)

 
  1. Abbreviations: IDC=invasive ductal cancer; ILC=invasive lobular cancer; SM=segmental mastectomy; TM=total mastectomy.
  2. aP-value calculated after excluded unknown category.
  3. bKruskal–Wallis equality-of-populations rank test.