Table 2 Top biofunctional pathways affected by miR-34c
From: The tumour suppressor miR-34c targets MET in prostate cancer cells
Category | Function annotation | P-value |
|---|---|---|
Cell death | Cell death of cell lines | 2.5E-07 |
Cell death | Cell death of tumor cell lines | 8.8E-07 |
Cell death | Apoptosis of cell lines | 2.3E-06 |
Cell death | Apoptosis of tumor cell lines | 4.8E-06 |
Cell death | Apoptosis of eukaryotic cells | 6.5E-06 |
Cell death | Cell death of eukaryotic cells | 6.8E-06 |
Cell death | Apoptosis | 1.1E-05 |
Cell cycle | Cell division process | 1.2E-05 |
Cellular growth and proliferation | Proliferation of tumor cells | 1.6E-05 |
Tumor morphology | Proliferation of tumor cells | 1.6E-05 |
Cancer | Ovarian cancer | 1.8E-05 |
Reproductive system disease | Ovarian cancer | 1.8E-05 |
Cell death | Cell death | 2.2E-05 |
Cellular development | Angiogenesis of cells | 2.8E-05 |
Organismal development | Angiogenesis of cells | 2.8E-05 |
Cardiovascular system development/function | Angiogenesis of cells | 2.8E-05 |
Cell-to-cell signaling and interaction | Formation of gap junctions | 3.0E-05 |
Cellular assembly and organization | Formation of gap junctions | 3.0E-05 |
Cell death | Cell death of breast cancer cell lines | 3.1E-05 |
Cellular movement | Invasion of cell lines | 3.2E-05 |
Infection mechanism | Replication of Herpesviridae | 3.7E-05 |
Cellular growth and proliferation | Proliferation of cancer cells | 4.5E-05 |
Tumor morphology | Proliferation of cancer cells | 4.5E-05 |
