Table 1 Chondrosarcoma cell lines

From: Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells

Cell Line

Tumour type

Grade

Gender

Age

Passage

TP53 a

IDH1 b

IDH2 b

Reference

SW1353

Solitary central

II

F

72

21

V203L

wt

R172S

Commercial (ATCC)

OUMS27

Solitary central

III

M

65

27

wt

wt

wt

Kunisada et al (1998)

CH2879

Solitary central

III

F

35

>80

wt

wt

wt

Gil-Benso et al (2003)

JJ012

Solitary central

II

M

39

9

G199V

R132G

wt

Scully et al (2000)

L835

Solitary central

III

M

55

50

wt

R132C

wt

van Oosterwijk et al (2012a)

L2975

Dedifferentiated

 

M

57

60

wt

R172W

wt

van Oosterwijk et al (2012a)

NDCS1

Dedifferentiated

 

M

38

60

C242S

wt

wt

Kudo et al (2007)

L3252

Dedifferentiated

 

F

52

30

wt

wt

wt

van Oosterwijk et al (2012a)

  1. aIDH mutations for used cell lines were described in Pansuriya et al (2011) and van Oosterwijk et al (2012a).
  2. bTP53 mutations for used cell lines were described in van Oosterwijk et al (2012a, 2012b).