Table 3 Protein expression in tumours using immunohistochemistry

From: Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells

  

Peripheral chondrosarcoma

 

Central chondrosarcoma

 

Osteochondroma

Grade I

Grade II

Grade III

Enchondroma

Grade I

Grade II

Grade III

pSrc

3/3 (100%)

12/13 (92%)

6/6 (100%)

3/3 (100%)

4/5 (80%)

21/24 (88%)

21/22 (96%)

10/10 (100%)

Src

1/7 (14%)

7/17 (41%)

8/8 (100%)

2/3 (67%)

4/7 (57%)

12/31 (39%)

12/31 (39%)

7/13 (54%)

Yes

0/7 (0%)

3/23 (13%)

0/10 (0%)

0/3 (0%)

0/7 (0%)

0/36 (0%)

3/30 (10%)

0/14 (0%)

Fyn

7/8 (88%)

16/20 (80%)

9/10 (90%)

3/3 (100%)

5/5 (100%)

17/35 (49%)

31/35 (89%)

13/14 (93%)

Lck

0/3 (0%)

1/23 (4%)

2/10 (20%)

0/3 (0%)

0/7 (0%)

1/38 (3%)

0/33 (0%)

2/13 (15%)

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