Table 1 Baseline characteristicsAbbreviation: ECOG=Eastern Cooperative Oncology Group

From: A phase-1b study of everolimus plus paclitaxel in patients with small-cell lung cancer

Characteristic

Total ( n =21)

Median age (years)

59

Gender

Male

19 (90%)

Female

2 (10%)

ECOG performance status

1

14 (67%)

2

7 (33%)

Prior therapies

Chemotherapy

Two prior regimens

15 (71%)

Three prior regimens

6 (29%)

Chest radiotherapy

6 (29%)

Brain radiotherapy

11 (52%)

Prophylactic

6 (29%)

Treatment

5 (24%)

Relapsing pattern after initial therapy a

Sensitive

9 (47%)

Refractory

12 (53%)

Number of metastatic organ(s)

One

10 (48%)

Two

7 (33%)

Three or more

4 (19%)

  1. aSensitive or refractory relapses were defined as relapses occurring more than or within 3 months, respectively, from completion of first-line chemotherapy.