Figure 2

Effects of PAF and a specific PAF receptor antagonist ABT-491 on the proliferation of prostate cancer cells. (A) Expression of PAF receptor (PAF-R) in LNCaP cells and PC-3 cells was determined by western blot. (B) Prostate cancer cells were exposed to increasing concentrations of ABT-491. (C) Prostate cancer cells were treated with increasing concentrations of PAF for 24 h. Values are presented as mean percent control±s.e.m. of six different experiments. *P<0.05 and **P<0.01 compared with control.