Table 1 Characteristics of CRC patients and a population-based comparison cohort matched by gender, age, year of diagnosis, and comorbidity, Denmark 1995–2010
CRC cohort | Population-based comparison cohort a | |||
|---|---|---|---|---|
Number | % | Number | % | |
Sex | ||||
Female | 27 665 | 49 | 132 537 | 49 |
Male | 29 298 | 51 | 139 133 | 51 |
Age at diagnosis/index (years) | ||||
0–59 | 10 285 | 18 | 51 467 | 19 |
60–69 | 14 541 | 26 | 70 613 | 26 |
70–79 | 18 547 | 33 | 87 444 | 32 |
80+ | 13 590 | 24 | 62 146 | 23 |
Year of diagnosis/index date | ||||
1995–1999 | 16 230 | 29 | 78 136 | 29 |
2000–2004 | 17 359 | 31 | 83 088 | 31 |
2005–2010 | 23 374 | 41 | 110 446 | 41 |
Stage of CRC | ||||
Non-metastatic | 37 381 | 66 | NA | — |
Metastatic | 12 687 | 22 | NA | — |
Unknown | 6895 | 12 | NA | — |
Cancer location | ||||
Colon | 37 859 | 67 | NA | — |
Rectal | 19 014 | 33 | NA | — |
Colon and rectal | 90 | 0.2 | NA | — |
Comorbidities included in the CCI | ||||
Myocardial infarction | 3270 | 5.7 | 13 825 | 5.1 |
Congestive heart failure | 2783 | 4.9 | 10 652 | 3.9 |
Peripheral vascular disease | 2322 | 4.1 | 9299 | 3.4 |
Cerebrovascular disease | 5014 | 8.8 | 21 852 | 8.0 |
Dementia | 594 | 1.0 | 2297 | 0.8 |
Chronic pulmonary disease | 4009 | 7.0 | 17 061 | 6.3 |
Connective tissue disease | 1567 | 2.8 | 6293 | 2.3 |
Ulcer disease | 3026 | 5.3 | 12 711 | 4.7 |
Mild liver disease | 478 | 0.8 | 1670 | 0.6 |
Diabetes type I and II | 3007 | 5.3 | 11 945 | 4.4 |
Haemiplegia | 100 | 0.2 | 252 | 0.1 |
Moderate to severe renal disease | 811 | 1.4 | 2557 | 0.9 |
Diabetes with end-organ failure | 1384 | 2.4 | 4901 | 1.8 |
Any tumour (excluding CRC) | 5037 | 8.8 | 22 517 | 8.3 |
Leukemia | 158 | 0.3 | 494 | 0.2 |
Lymphoma | 295 | 0.5 | 1010 | 0.4 |
Moderate to severe liver disease | 113 | 0.2 | 311 | 0.1 |
Metastatic solid tumour | 519 | 0.9 | 1944 | 0.7 |
AIDS | 10 | 0.0 | 25 | 0.0 |
Diseases not originally included in the CCI | ||||
Atrial fibrillation/flutter | 1164 | 2.0 | 4213 | 1.6 |
Obesity | 1197 | 2.1 | 4320 | 1.6 |
CCI scores b | ||||
0 (No comorbidity) | 34 918 | 61 | 172 041 | 63 |
1 (Low comorbidity) | 9747 | 17 | 47 139 | 17 |
2–3 (Moderate comorbidity) | 9522 | 17 | 44 788 | 17 |
4+ (High comorbidity) | 2776 | 4.9 | 7702 | 2.8 |
