Table 1 PICT1 expression and clinocopathologic factors in gastric cancer patients with wild-type TP53

From: PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression

 

PICT1 low expression ( n =35)

PICT1 high expression ( n =35)

 

Factors

Number

%

Number

%

P -value

Age (mean±s.d.)

66.5±2.00

 

64.5±2.00

 

0.477

Gender

Male

22

62.9

21

60.0

0.806

Female

13

37.1

14

40.0

 

Histological grade

Well and moderately

17

48.6

18

51.4

0.811

Poorly and Signet

18

51.4

17

48.6

 

Tumour depth a

m, sm, mp

21

60.0

12

34.3

0.03*

ss, se, si

14

40.0

22

65.7

 

Lymph node metastasis

Absent

16

45.7

17

48.6

0.811

Present

19

54.3

18

51.4

 

Lymphatic invasion

Absent

13

37.1

9

25.7

0.302

Present

22

62.9

26

74.3

 

Venous invasion

Absent

32

91.4

26

74.3

0.052

Present

3

8.6

9

25.7

 

Peritoneal dissemination

Absent

34

97.1

30

85.7

0.075

Present

1

2.9

5

14.3

 

Stage

Stages I, II

26

74.3

19

54.3

0.081

Stages III, IV

9

25.7

16

45.7

 
  1. *P<0.05.
  2. aTumour invasion of mucosa (m), submucosa (sm), muscularis propria (mp), subserosa (ss), penetration of serosa (se), and invasion of adjacent strucures (si).