Table 1 Incidence rate (IR) changes in prostate cancer diagnostic characteristic between 2000–2005 and 2006–2010
Domain | IR 2000–2005 | IR 2006–2010 | Change | s.e. | 95% CI | P -value | Trend | |
|---|---|---|---|---|---|---|---|---|
Total cases | 365.11 | 416.73 | 51.62 | 5.61 | 62.62 | 40.62 | <0.00001 | Increase |
Metastasis | 58.2 | 51.13 | −7.08 | 2.09 | −2.98 | −11.18 | 0.0007 | Decrease |
PSA | ||||||||
PSA<10 | 70.54 | 128.22 | 57.68 | 2.85 | 63.26 | 52.1 | <0.00001 | Increase |
PSA 10–20 | 69.66 | 77.3 | 7.64 | 2.43 | 12.41 | 2.87 | 0.0016 | Increase |
PSA>20 | 61.37 | 90.87 | 29.5 | 2.48 | 34.37 | 24.63 | <0.00001 | Increase |
T-stage | ||||||||
T1–T2 | 173.81 | 255.68 | 81.87 | 4.17 | 90.05 | 73.69 | <0.00001 | Increase |
T3–T4 | 27.77 | 40.72 | 12.95 | 1.67 | 16.22 | 9.69 | <0.00001 | Increase |
Gleason grade | ||||||||
⩽6 | 91.51 | 81.35 | −10.16 | 2.63 | −5 | −15.32 | 0.0001 | Decrease |
7 | 65.54 | 143.18 | 77.64 | 2.92 | 83.37 | 71.92 | <0.00001 | Increase |
8–10 | 44.53 | 71.86 | 27.33 | 2.17 | 31.6 | 23.07 | <0.00001 | Increase |
Risk group | ||||||||
Low | 38.42 | 46.95 | 8.53 | 1.86 | 12.17 | 4.9 | <0.00001 | Increase |
Intermediate | 63.63 | 115.99 | 52.37 | 2.71 | 57.67 | 47.07 | <0.00001 | Increase |
High | 99.6 | 133.49 | 33.88 | 3.07 | 39.9 | 27.86 | <0.00001 | Increase |