Table 1 Patient and treatment characteristics

From: Allogeneic stem cell transplantation for patients with advanced rhabdomyosarcoma: a retrospective assessment

 

RMS patients ( n =30)

 

Number

Fraction

Age at diagnosis (years)

0–9

8

0.27

10–19

19

0.63

20–29

3

0.10

Gender

Male

17

0.57

Female

13

0.43

Date of diagnosis

 <2000

4

0.13

2000

26

0.87

Date of last allo-SCT

 <2000

1

0.03

2000

29

0.97

RMS subtype

 Alveolar

23

0.77

 Embryonal

3

0.10

 Unknown

4

0.13

First-line local treatment modality

 Surgery only

5

0.17

 Irradiation only

9

0.30

 Surgery+Irradiation

9

0.30

 None

5

0.17

 Unknown

2

0.07

Stage at diagnosis

Stage II at Diagnosis

1

0.03

Stage III at Diagnosis

3

0.10

Stage IV at Diagnosis

23

0.77

Unknown

3

0.10

Status at allo-SCT

 CR

24

0.80

 Residual disease

6

0.20

Previous graft

No previous graft

20

0.67

Allogeneic graft once

1

0.03

Autologous graft(s)

9

0.30

Transplant conditioning regimen

RIC

20

0.67

HDC

10

0.33

Total body irradiation

Yes (all 2 Gy)

4

0.13

No

26

0.87

Graft source for allo-SCT

BM

16

0.53

PB

10

0.33

CB

4

0.13

Donor HLA match

Matched related

17

0.57

Matched unrelated

6

0.20

Mismatcheda

7

0.23

DLI after allo-SCT

Yes

3

0.10

No

26

0.87

Unknown

1

0.03

  1. Abbreviations: allo-SCT=allogeneic stem cell transplantation; BM=bone marrow; CB=cord blood; CR=complete remission; DLIs=donor lymphocyte infusions; HDC=high-dose chemotherapy; PB=peripheral blood; PD=progressive disease; PR=partial remission; RIC=reduced-intensity chemotherapy; RMS=rhabdomyosarcoma.
  2. a1 allele mismatch in HLA class 1 and/or HLA class 2.