Table 1 STA-ET-7.2-specific genes related to p53 and apoptosis

From: Variability in functional p53 reactivation by PRIMA-1Met/APR-246 in Ewing sarcoma

Gene name

EG

Name

Log2 fold change a

MST4

51765

Serine/threonine protein kinase MST4

−4.31

PCDH7

5099

Protocadherin 7

−2.72

TMEM35

59353

Transmembrane protein 35

−2.05

ENPP4

22875

Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)

−2.01

RGS4

5999

Regulator of G-protein signaling 4

−1.67

FAIM

55179

Fas apoptotic inhibitory molecule

−1.65

ARL4A

10124

ADP-ribosylation factor-like 4A

−1.5

MYCN

4613

v-Myc myelocytomatosis viral-related oncogene, neuroblastoma derived (avian)

−1.29

OBSL1

23363

Obscurin-like 1

−1.27

ELOVL6

79071

ELOVL fatty acid elongase 6

−1.24

PIR

8544

Pirin (iron-binding nuclear protein)

−1.22

MAP7D2

256714

MAP7 domain containing 2

−1.21

VEGFA

7422

Vascular endothelial growth factor A

−1.15

TOX

9760

Thymocyte selection-associated high mobility group box

−1.14

EPHA2

1969

EPH receptor A2

−1.14

CANX

821

Calnexin

−1.07

CMBL

134147

Carboxymethylenebutenolidase homolog (Pseudomonas)

−1.04

SELENBP1

8991

Selenium binding protein 1

−1.03

PKIB

5570

Protein kinase (cAMP-dependent, catalytic) inhibitor beta

1

CACNA1G

8913

Calcium channel, voltage-dependent, T type, alpha 1G subunit

1.02

CRISPLD2

83716

Cysteine-rich secretory protein LCCL domain containing 2

1.02

HOXB2

3212

Homeobox B2

1.03

GLIPR2

152007

GLI pathogenesis-related 2

1.03

COL9A3

1299

Collagen, type IX, alpha 3

1.03

HSPA12A

259217

Heat shock 70-kDa protein 12A

1.13

GSN

2934

Gelsolin

1.14

KIAA1217

56243

KIAA1217

1.16

SATB1

6304

SATB homeobox 1

1.17

APOL6

80830

Apolipoprotein L, 6

1.2

GNAQ

2776

Guanine nucleotide binding protein (G protein), q polypeptide

1.3

KANK1

23189

KN motif and ankyrin repeat domains 1

1.31

FRY

10129

Furry homolog (Drosophila)

1.33

EGFR

1956

Epidermal growth factor receptor

1.36

RHOB

388

Ras homolog family member B

1.43

PCSK9

255738

Proprotein convertase subtilisin/kexin type 9

1.44

ANK3

288

Ankyrin 3, node of Ranvier (ankyrin G)

1.52

FMOD

2331

Fibromodulin

1.62

FST

10468

Follistatin

1.72

NTN1

9423

Netrin 1

1.82

PENK

5179

Proenkephalin

1.89

ADM

133

Adrenomedullin

2.24

INSM1

3642

Insulinoma-associated 1

2.37

  1. aValues for each gene are log 2 fold change of the STA-ET-7.2 cell line vs the average of STA-ET-7.1 and STA-ET-7.3 cell lines.