Table 4 Type-specific HPV prevalences with exact binomial 95% confidence intervals (CI) by histologically confirmed cervical lesion
Histological diagnosis | ||||||||
---|---|---|---|---|---|---|---|---|
No lesion ( n =181) | CIN 1 ( n =71) | CIN 2 ( n =104) | CIN 3+ ( n =63) | |||||
Type(s) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) |
HPV 16 | 28 | 15.5 (10.5–21.6) | 11 | 15.5 (8.0–26.0) | 40 | 38.5 (29.1–48.5) | 38 | 60.3 (47.2–72.4) |
HPV 18 | 12 | 6.6 (3.5–11.3) | 4 | 5.6 (1.6–13.8) | 6 | 5.8 (2.1–12.1) | 2 | 3.2 (0.4–11.0) |
HPV 31 | 20 | 11.0 (6.9–16.5) | 4 | 5.6 (1.6–13.8) | 24 | 23.1 (15.4–32.4) | 8 | 12.7 (5.6–23.5) |
HPV 33 | 13 | 7.2 (3.9–12.0) | 5 | 7.0 (2.3–15.7) | 6 | 5.8 (2.1–12.1) | 5 | 7.9 (2.6–17.6) |
HPV 35 | 4 | 2.2 (0.6–5.6) | 2 | 2.8 (0.3–9.8) | 4 | 3.8 (1.1–9.6) | 1 | 1.6 (0.04–8.5) |
HPV 39 | 11 | 6.1 (3.1–10.6) | 3 | 4.2 (0.9–11.9) | 4 | 3.8 (1.1–9.6) | 1 | 1.6 (0.04–8.5) |
HPV 45 | 8 | 4.4 (1.9–8.5) | 3 | 4.2 (0.9–11.9) | 3 | 2.9 (0.6–8.2) | 1 | 1.6 (0.04–8.5) |
HPV 51 | 19 | 10.5 (6.4–15.9) | 13 | 18.3 (10.1–29.3) | 4 | 3.8 (1.1–9.6) | 1 | 1.6 (0.04–8.5) |
HPV 52 | 10 | 5.5 (2.7–9.9) | 1 | 1.4 (0.04–7.6) | 7 | 6.7 (2.7–13.4) | 5 | 7.9 (2.6–17.6) |
HPV 56 | 18 | 9.9 (6.0–15.3) | 5 | 7.0 (2.3–15.7) | 2 | 1.9 (0.2–6.8) | 2 | 3.2 (0.4–11.0) |
HPV 58 | 11 | 6.1 (3.1–10.6) | 4 | 5.6 (1.6–13.8) | 7 | 6.7 (2.7–13.4) | 3 | 4.8 (1.0–13.3) |
Group 1/2 Aa | 136 | 75.1 (68.2–81.3) | 51 | 71.8 (59.9–81.9) | 88 | 84.6 (76.2–90.9) | 57 | 90.5 (80.4–96.4) |
Group 2Bb | 23 | 12.7 (8.2–18.5) | 13 | 18.3 (10.1–29.3) | 4 | 3.8 (1.1–9.6) | 1 | 1.6 (0.04–8.5) |
Any HPV | 163 | 90.1 (84.7–94.0) | 65 | 91.5 (82.5–96.8) | 92 | 88.5 (80.7–93.9) | 58 | 92.1 (82.4–97.4) |