Table 3 Brief description of patients with nodal metastasis falsely classified as low risk

From: Preoperative nomogram for the identification of lymph node metastasis in early cervical cancer

Characteristics

Patient 1

Patient 2

Patient 3

Patient 4

Preoperative assessment

Age, years

62

47

46

32

FIGO stage

IB1

IB1

IB1

IB1

Histology

Squamous

Squamous

Squamous

Squamous

Serum SCC Ag (ng ml−1)

0.83

0.35

1.4

0.9

Tumour size by MRI (cm)

2

0a

0a

0a

PM invasion by MRI

Absent

Absent

Absent

Absent

LNM by PET/CT

Absent

Absent

Absent

Absent

Postoperative assessment

Histology

Squamous

Squamous

Squamous

Squamous

Tumour size (cm)

4.0

1.5

1.5

1.3

Depth of stromal invasion (mm)

6

2

10

6

LVSI

Present

Absent

Present

Present

PM invasion

Present

Absent

Absent

Absent

LNM

Yes (1 of 34)

Yes (1 of 25)

Yes (1 of 18)

Yes (4 of 42)

Location of metastatic LN

Left external

Right external

Right internal

Left obturator

Right external

Largest diameter of metastatic LN

0.7 mm

6 mm

<1 mm

7 mm

Para-aortic LNM

No (0 of 1)

NA

No (0 of 1)

No (0 of 1)

Adjuvant treatment

CCRTb

CCRTb

CCRTb

CCRTb

Recurrence

No

No

No

No

Progression-free survival

21 months

32 months

6 months

40 months

  1. Abbreviations: FIGO=International Federation of Gynecology and Obstetrics; LN=lymph node; LNM=LN metastasis; LVSI=lymphovascular space invasion; MRI=magnetic resonance imaging; NA, not applicable; PET/CT=positron emission tomography/computed tomography; PM=parametrial; SCC Ag=squamous cell carcinoma antigen.
  2. No visible residual tumour in the uterine cervix.
  3. bConcurrent chemoradiation (weekly cisplatin regimen).