Figure 6 | British Journal of Cancer

Figure 6

From: Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer

Figure 6

CHKA -silenced cells display reduced motility and invasion. Cells migrating through the membrane were measured by (A). RFU of CyQUANT dye binding to cellular nucleic acids in the lysates or (B). Odyssey infrared laser scanner quantification after SRB staining. In the graphs is reported the percentage of inhibition of migration in CHKA-silenced INTOV11 and SKOV3 cells as compared with their relative controls (oligo-treated cells), to which significance is referred. Data are the mean±s.d. of three to six independent experiments. (C): upper panels. photographs of a representative experiment of the matrigel-coated membrane invading cells. Magnification × 200. lower panel: mean relative percentage±s.d. of invasion capability calculated respect to control oligo-treated cells set to 100%.

Back to article page