Table 4 Hazard ratios for death (analysis from time of diagnosis)
From: Treatment decisions and survival for people with small-cell lung cancer
Survival from diagnosis | Total patients N =15 091 | Deaths n =10 041 | % | HR | 95% CI | Adjusted HR a | 95% CI |
|---|---|---|---|---|---|---|---|
Townsend quintile | |||||||
1 (Least deprived) | 2111 | 1981 | 93.8 | 1.00 | 1.00 | ||
2 | 2704 | 2558 | 94.6 | 1.02 | 0.96–1.08 | 1.03 | 0.98–1.10 |
3 | 2958 | 2788 | 94.3 | 1.02 | 0.96–1.08 | 1.01 | 0.95–1.07 |
4 | 3307 | 3109 | 94.0 | 1.01 | 0.95–1.06 | 1.03 | 0.98–1.09 |
5 (Most deprived) | 3738 | 3517 | 94.1 | 0.99 | 0.94–1.05 | 1.02 | 0.96–1.08 |
Missing | 273 | 262 | 96.0 | 1.69 | 1.49–1.93 | 1.39 | 1.22–1.58 |
Route of referral | |||||||
Emergency admission | 2323 | 2246 | 96.7 | 1.69 | 1.61–1.78 | 1.30 | 1.24–1.37 |
General Practitioner | 7267 | 6738 | 92.7 | 1.00 | 1.00 | ||
Consultant referral | 2729 | 2566 | 94.0 | 1.19 | 1.14–1.25 | 1.01 | 0.96–1.06 |
Other (inc private) | 887 | 836 | 94.3 | 1.18 | 1.10–1.27 | 1.03 | 0.96–1.11 |
Emergency Department | 1120 | 1086 | 97.0 | 1.66 | 1.56–1.77 | 1.29 | 1.21–1.37 |
Missing | 765 | 743 | 97.1 | 1.26 | 1.17–1.36 | 1.12 | 1.04–1.21 |
Radiotherapy | |||||||
No chemotherapy | 4509 | 4448 | 98.6 | 1.00 | 1.00 | ||
Chemotherapy only | 9590 | 8962 | 93.5 | 0.28 | 0.27–0.29 | 0.35 | 0.34–0.37 |
Chemo-radiotherapy | 992 | 805 | 81.1 | 0.16 | 0.15–0.18 | 0.26 | 0.24–0.28 |
Chemotherapy cycles | |||||||
No chemotherapy | 4509 | 4448 | 98.6 | 1.00 | 1.00 | ||
1–3 cycles | 3228 | 3115 | 96.5 | 0.45 | 0.43–0.47 | 0.54 | 0.52–0.57 |
⩾4 cycles | 5540 | 4936 | 89.1 | 0.20 | 0.19–0.21 | 0.25 | 0.24–0.27 |
NLCA record only | 1814 | 1716 | 94.6 | 0.31 | 0.29–0.33 | 0.39 | 0.37–0.41 |
Time to treatment | |||||||
<18 days | 5137 | 4834 | 94.1 | 1.00 | 1.00 | ||
⩾18 days | 5445 | 4933 | 90.6 | 0.80 | 0.77–0.83 | 0.84 | 0.81–0.88 |
No chemotherapy | 4509 | 4448 | 98.6 | 3.30 | 3.17–3.44 | 2.64 | 2.52–2.76 |
Trust first seen | |||||||
Non-chemotherapy trust | 4276 | 4011 | 93.8 | 1.00 | 1.00 | ||
Chemotherapy trust | 10 779 | 10 171 | 94.4 | 1.01 | 0.97–1.04 | 0.99 | 0.95–1.02 |
Missing/trust that saw <20 cases | 36 | 33 | 91.7 | 0.99 | 0.70–1.39 | 0.93 | 0.66–1.32 |
