Table 2 Details of prior therapy (Phase II patients)

From: Sorafenib and irinotecan (NEXIRI) as second- or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: a multicentre Phase I/II trial

 

Patients, N= 54

%

Type of prior therapy

Surgery for primary tumour

47

87.0

Surgery for metastases

17

31.5

Adjuvant chemotherapy

24

44.4

Palliative chemotherapy

54

100.0

 1 Line

7

12.9

 2 Lines

11

20.4

 3 Lines

15

27.8

4 Lines

21

38.9

Radiotherapy

25

46.3

Failure of previous medication

5-FU

54

100.0

Irinotecan

54

100.0

Oxaliplatin

52

96.3

Bevacizumab

49

90.7

Cetuximab

9

16.7