Figure 2
From: Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats
CCX662 increases post-IR survival time in ENU-treated rats. Rats were exposed to the carcinogen ENU in utero and, on day 115, given 20 Gy whole-brain IR. Immediately following IR, rats were infused with CCX662 or its vehicle for 4 weeks. CCX662 significantly increased post-IR median survival time (**P=0.0003 compared with vehicle, log-rank test; n=4–6 rats).
