Figure 4
From: Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats
CXCR7 expression increases with glioma tumour grade. A multi-grade glioma array was stained by IHC with the CXCR7 mAb 11G8. (A) The incidence of 11G8 staining, on the tumour cells and/or tumour-associated vasculature, increased with tumour grade. (B) IHC staining of representative tumours with 11G8 (right column) or an isotype control mAb (left column). Note the staining of tumour cells (middle row) and tumour-associated vasculature (bottom row) in the Grade IV tumours by 11G8. Magnification × 200.
