Figure 4 | British Journal of Cancer

Figure 4

From: Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives

Figure 4

Aza-dC downregulates the expression of stem cell-associated genes in pluripotent stem cells through DNMT3B. Expression of OCT4, NANOG and SOX2 was assessed by RT-qPCR upon treatments by doxycycline (Dox) to knockdown DNMT3B and by Aza-dC in (A) N2102Ep, (B) TERA1, (C) NTERA2 and (D) H7 ES cells. Data are represented as mean±s.d.; n=3; *P<0.05.

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