Table 2 Joint associationsa of smoking and family history of breast cancer with postmenopausal breast cancer risk

From: Cigarette smoking and postmenopausal breast cancer risk in a prospective cohort

 

Family history of breast cancer

 

No

Yes

Smoking status

Never

 HR (95% CI)b

1.00 (reference)

1.56 (1.42–1.71)

 Cases

2551

617

 Person-years

689 876

103 053

Former

 HR (95% CI)b

1.08 (1.01–1.14)

1.60 (1.45–1.77)

 Cases

2289

506

 Person-years

558 410

83 133

Current

 HR (95% CI)b

1.24 (1.14–1.34)

1.49 (1.27–1.75)

 Cases

1023

174

 Person-years

242 761

33 628

  1. Abbreviations: CI=confidence interval; HR=hazard ratio.
  2. aP-interaction=0.03.
  3. bAdjusted for age at study entry, education level, race/ethnicity, age at menarche, nulliparity/age at first birth, age at and type of menopause, menopausal hormone therapy use, grams of alcohol consumed per day, BMI, frequency of vigorous physical activity, and previous breast biopsy.
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