Table 3 Factors associated with mastectomy in patients with very early breast cancera
From: Spectrum of very early breast cancer in a setting without organised screening
Characteristics | Mastectomy (n =591) | Breast conserving surgery (n =527) | Univariable odds ratio for mastectomy (95% CI) | Multivariable odds ratio for mastectomy b (95% CI) |
|---|---|---|---|---|
Age, in years, medianc | 55 (48,64) | 49 (43,56) | 1.05 (1.04–1.06)d | 1.02 (1.01–1.04)d |
Race, n (%) | ||||
Chinese | 476 (57.6) | 350 (42.4) | 1.00 | 1.00 |
Malay | 56 (35.9) | 100 (64.1) | 0.41 (0.29–0.59)d | 0.41 (0.27–0.62)d |
Indian | 51 (45.9) | 60 (54.1) | 0.63 (0.42–0.93)d | 0.55 (0.35–0.87)d |
Others | 8 (32.0) | 17 (68.0) | 0.35 (0.15–0.81)d | 0.54 (0.21–1.40) |
Marital status, n (%) | ||||
Married | 491 (54.3) | 414 (45.7) | 1.31 (0.92–1.85) | — |
Not married | 70 (47.6) | 77 (52.4) | 1.00 | — |
Not known | 30 | 36 | — | |
Parity, n (%) | ||||
Nulliparous | 86 (48.9) | 90 (51.1) | 1.00 | 1.00 |
1–2 children | 162 (48.5) | 172 (51.5) | 0.99 (0.68–1.42) | 0.77 (0.51–1.18) |
⩾3 children | 283 (60.4) | 175 (39.6) | 1.69 (1.19–2.40)d | 1.32 (0.87–2.00) |
Unknown | 60 | 90 | ||
Menopausal status, n (%) | ||||
Premenopausal | 198 (39.6) | 302 (60.4) | 1.00 | 1.00 |
Postmenopausal | 355 (63.7) | 202 (36.3) | 2.68 (2.09–3.44)d | 1.96 (1.27–3.02)d |
Unknown | 38 | 23 | ||
Year of diagnosis, n (%) | ||||
1993–1997 | 37 (55.2) | 30 (44.8) | 1.00 | — |
1998–2002 | 89 (43.8) | 114 (56.2) | 0.63 (0.36–1.10) | — |
2003–2007 | 215 (53.3) | 188 (46.7) | 0.93 (0.55–1.56) | — |
2008–2011 | 248 (56.0) | 195 (44.0) | 1.03 (0.62–1.73) | — |
Unknown | 2 | 0 | ||
Tumour size, in cm, medianc | 1.5 (1.0,2.0) | 1.4 (0.8,1.7) | 1.21 (1.02–1.45)d | 1.22 (1.01–1.48)d |
Lymphovascular invasion | ||||
Present | 144 (57.4) | 107 (42.6) | 1.22 (0.91–1.64) | |
Absent | 338 (52.4) | 307 (47.6) | 1.00 | |
Unknown | 109 | 113 | ||
