Figure 7

Effects of Ad.5/3-vec, Ad.5/3- mda- 7 and BI-69A11 on invasion of HT29 colon carcinoma cells. (A) Photomicrographs of HT29 cell invasion assays following BI-69A11 and Ad.5/3-mda-7 infection alone and in combination. HT29 cells were treated with 0.5 μ M BI-96A11 and/or Ad.5/3-mda-7 (25 pfu per cell) for 48 h. Photographs were taken at 10 × magnification. (B) Data represent the average percentage of cells (±s.d.) invading the Boyden chamber inserts coated with Matrigel of three different experiments, each performed in triplicate; **P<0.01 and ***P<0.001 represent level of significance with respect to Ad.5/3-vec.