Figure 2

Immunohistochemical analysis in human HCCs. Representative example of immunohistochemistry for SERPINB3, TGF-β1 and β-catenin, counterstained with hematoxylin, in serial sections of HCC specimens showing low SERPINB3 mRNA (A) or high SERPINB3 mRNA (B). Original magnification are reported. (C) Graphical representation of the quantitative analysis of each staining expressed as the mean of percentage of positive parenchyma staining per area in analysed tumour samples. Bars represent s.d. values. *P<0.0001 (HCCs with low SERPINB3 mRNA vs HCCs with high SERPINB3 mRNA).