Table 1 Distribution of comorbidities among basal cell carcinoma cases and their matched controls

From: Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities

 

BCC cases ( n =57 121), n (%)

BCC-free controls ( n =57 121), n (%)

OR crude (95% CI)

Diseases of internal organs

COPD

2663 (4.7)

2922 (5.1)

0.90 (0.86–0.96)

Diabetes mellitus

5009 (8.8)

5709 (10.0)

0.86 (0.83–0.90)

Hypertension

22 235 (38.9)

21 807 (38.2)

1.04 (1.01–1.06)

Gout

3660 (6.4)

3483 (6.1)

1.06 (1.01–1.11)

Rheumatoid arthritis

1571 (2.8)

1322 (2.3)

1.20 (1.11–1.29)

Inflammatory bowel disease

729 (1.3)

589 (1.0)

1.24 (1.11–1.39)

Depression

8784 (15.4)

8758 (15.3)

1.00 (0.97–1.04)

Schizophrenia

271 (0.5)

381 (0.7)

0.71 (0.61–0.83)

Dementia

672 (1.2)

945 (1.7)

0.70 (0.63–0.77)

Malignancies (excl. skin cancer)

5247 (9.2)

4015 (7.0)

1.35 (1.29–1.41)

Solid organ transplantation

205 (0.4)

41 (0.1)

5.10 (3.63–7.16)

Skin diseases

Atopic dermatitis

3761 (6.6)

3305 (5.8)

1.16 (1.10–1.22)

Seborrhoeic dermatitis

3514 (6.2)

2686 (4.7)

1.34 (1.27–1.41)

Skin mycoses

8560 (15.0)

7263 (12.7)

1.22 (1.18–1.27)

Bacterial skin infections

3948 (6.9)

3388 (5.9)

1.18 (1.13–1.24)

Warts

5462 (9.6)

3642 (6.4)

1.58 (1.51–1.65)

Herpes infection

6923 (12.1)

6236 (10.9)

1.13 (1.09–1.17)

Psoriasis

2480 (4.3)

2319 (4.1)

1.07 (1.01–1.14)

Rosacea

2346 (4.1)

1671 (2.9)

1.43 (1.34–1.53)

Cutaneous malignant melanoma

810 (1.4)

332 (0.6)

2.46 (2.16–2.80)

  1. Abbreviations: BCC=basal cell carcinoma; CI=confidence interval; COPD=chronic obstructive pulmonary disease; OR=odds ratio.