Table 1 Association between clinico-pathological characteristics of metastatic colorectal cancer patients and immunohistochemical data
pACC score | pAMPK score | ||||||
|---|---|---|---|---|---|---|---|
Characteristics | N (%) | â©˝5 ( N =15) | >5 ( N =33) | P -value | â©˝5 ( N =14) | >5 ( N =34) | P -value |
Gender | 0.751 | 1.00 | |||||
Male | 29 (60.4) | 10 | 19 | 8 | 21 | ||
Female | 19 (39.6) | 5 | 14 | 6 | 13 | ||
Age at diagnosis (years) | 0.757 | 0.756 | |||||
â©˝65 | 25 (52.1) | 7 | 18 | 8 | 17 | ||
>65 | 23 (47.9) | 8 | 15 | 6 | 17 | ||
Primary site | 0.724 | 0.729 | |||||
Colon | 32 (66.7) | 10 | 22 | 9 | 23 | ||
Rectum | 14 (29.2) | 3 | 11 | 3 | 11 | ||
Colon and rectuma | 2 (4.2) | — | — | — | — | ||
Site of metastasis | 0.742 | 0.328 | |||||
Liver | 16 (33.3) | 4 | 12 | 3 | 13 | ||
Other | 32 (66.7) | 11 | 21 | 11 | 21 | ||
Synchronous metastasis | 0.239 | 1.00 | |||||
Yes | 39 (81.2) | 14 | 25 | 12 | 27 | ||
No | 9 (18.7) | 1 | 8 | 2 | 7 | ||
KRAS wildtype | 0.755 | 1.00 | |||||
Yes | 22 (45.8) | 8 | 14 | 6 | 16 | ||
No | 24 (50.0) | 7 | 17 | 7 | 17 | ||
Unknowna | 2 (4.2) | — | — | — | — | ||
ECOG-PS | 0.031 | 0.294 | |||||
0 | 36 (75.0) | 8 | 28 | 9 | 27 | ||
1 | 12 (25.0) | 7 | 5 | 5 | 7 | ||
Ablation/resection of metastasis | 0.004 | 0.206 | |||||
Yes | 28 (58.3) | 4 | 24 | 6 | 22 | ||
No | 20 (41.7) | 11 | 9 | 8 | 12 | ||
Lines of treatment | 1.00 | 1.00 | |||||
1 | 9 (18.7) | 3 | 6 | 3 | 6 | ||
â©ľ2 | 39 (81.2) | 12 | 27 | 11 | 28 | ||
Carcino-embrionic antigen>30 | 1.00 | 0.321 | |||||
Yes | 16 (33.3) | 5 | 11 | 3 | 13 | ||
No | 31 (64.6) | 10 | 21 | 11 | 20 | ||
Unknowna | 1 (2.1) | — | — | — | — | ||
