Table 2 Estimated 1-year overall survival and 95% confidence intervals by patient characteristics
Characteristics | N (%) | N . failed | 1-year overall survival (95% CI) | P -value |
|---|---|---|---|---|
Gender | 0.964 | |||
Male | 29 | 15 | 82.7 (63.4–92.4) | |
Female | 19 | 11 | 89.5 (64.1–97.2) | |
Age at diagnosis (years) | 0.907 | |||
⩽65 | 25 | 13 | 80.0 (58.4–91.1) | |
>65 | 23 | 13 | 91.3 (69.5–97.7) | |
Primary site | 0.909 | |||
Colon | 32 | 16 | 84.4 (66.4–93.2) | |
Rectum | 14 | 8 | 92.8 (59.1–99.0) | |
Colon and rectuma | 2 | 2 | — | |
Site of metastasis | 0.812 | |||
Liver | 16 | 9 | 93.7 (63.2–99.1) | |
Other | 32 | 17 | 81.2 (62.9–91.1) | |
Synchronous metastasis | 0.858 | |||
Yes | 39 | 20 | 84.6 (68.9–92.7) | |
No | 9 | 6 | 88.9 (43.3–98.3) | |
KRAS wildtype | 0.818 | |||
Yes | 22 | 11 | 81.8 (58.5–92.7) | |
No | 24 | 13 | 91.7 (70.6–97.8) | |
Unknowna | 2 | 1 | — | |
ECOG-PS | 0.001 | |||
0 | 36 | 16 | 94.4 (79.6–98.6) | |
1 | 12 | 10 | 58.3 (27.0–80.1) | |
Ablation/ resection metastasis | 0.001 | |||
Yes | 28 | 11 | 92.8 (74.3–98.2) | |
No | 20 | 15 | 75.0 (50.0–88.7) | |
Lines of treatment | 0.050 | |||
1 | 9 | 6 | 44.4 (13.6–71.9) | |
⩾2 | 39 | 20 | 94.9 (81.0–98.7) | |
Score pACC | 0.0007 | |||
⩽5 | 15 | 12 | 66.7 (37.5–84.5) | |
>5 | 33 | 14 | 93.9 (77.9–98.4) | |
Score pAMPK | 0.0002 | |||
⩽5 | 14 | 12 | 71.4 (40.6–88.2) | |
>5 | 34 | 14 | 91.2 (75.1–97.1) | |
Carcino-embrionic antigen >30 | 0.004 | |||
Yes | 16 | 12 | 75.0 (46.3–89.8) | |
No | 31 | 14 | 90.3 (72.9–96.8) | |
Unknowna | 1 | 1 | — |
