Table 1 Distribution of clinicopathological features by HIF-1α expression

From: Expression of hypoxia-inducible factor-1α predicts benefit from hypoxia modification in invasive bladder cancer

Variable

HIF-1 α <19

HIF-1 α19

P

Gender

 Male

54 (47)

60 (53)

0.18

 Female

15 (65)

8 (35)

 

Age (years)

 <75

38 (58)

27 (42)

0.1

75

31 (43)

41 (57)

 

Stage

 1

2 (40)

3 (60)

0.91

 2

51 (50)

50 (50)

 

 3

14 (54)

12 (46)

 

 4a

2 (40)

3 (60)

 

TURBT

 Complete

24 (46)

28 (54)

0.31

 Partial

22 (47)

25 (53)

 

 Biopsy

21 (62)

13 (38)

 

Necrosis

 Absent

38 (59)

26 (41)

0.07

 Present

31 (42)

42 (58)

 

Growth pattern

 Papillary

7 (50)

7 (50)

0.4

 Solid

37 (56)

29 (44)

 

 Both

25 (44)

32 (56)

 

CIS

 Absent

45 (46)

52 (54)

0.21

 Present

24 (60)

16 (40)

 

Hb (g dl−1)

 <14

43 (57)

33 (63)

0.15

14

26 (43)

35 (57)

 

CAIX

 0

34 (65)

18 (35)

0.004

 >0

30 (38)

49 (62)

 

GLUT1

 <100

36 (60)

24 (40)

0.006

100

22 (34)

43 (66)

 
  1. Abbreviations: CAIX=carbonic anhydrase IX; CIS=carcinoma in situ; Hb=haemoglobin; HIF-1α=hypoxia-inducible factor-1α; TURBT=transurethral resection of bladder tumour.