Figure 2

Kaplan–Meier curves for survival according to NLR and treatment course. (A) OS and (C) PFS stratified by NLR at diagnosis and after one cycle of chemotherapy. Patients with high NLR both at diagnosis and after one cycle of chemotherapy showed worse OS and PFS than patients with low or high NLR at diagnosis and low NLR after one cycle of chemotherapy (P<0.001 and P=0.007, respectively). (B) OS and (D) PFS stratified by NLR at diagnosis and at disease progression. Among patients with low NLR at diagnosis, patients with high NLR at disease progression showed worse OS than patients with low NLR at disease progression (P=0.033). Abbreviations: Dx=at diagnosis; NLR=neutrophil-to-lymphocyte ratio; OS=overall survival; PD=at disease progression; PFS=progression-free survival; 1 cycle=after 1 cycle of chemotherapy.