Table 6 HPV status in relation to patient and tumour characteristics (n=44)
Patient and tumour characteristics | HPV positive N(%) | HPV negative N(%) | P -value |
|---|---|---|---|
Mean age at diagnosis (years) | 73 (range 51–89) | 68 range (32–84) | |
History of CIN | |||
Yes | 7 (44) | 9 (56) | 1.00 |
No | 12 (43) | 16 (57) | |
Previous gynaecological malignancy | |||
Yes | 3 (50) | 3 (50) | 1.00 |
No | 16 (42) | 22 (58) | |
Hysterectomy before diagnosis | |||
Yes | 8 (47) | 9 (53) | 0.76 |
No | 11 (41) | 16 (59) | |
Histopathological grade ( n =43) | |||
Well | 0 (0) | 8 (100) | 0.011 |
Moderate | 13 (62) | 8 (38) | |
Poor | 6 (43) | 8 (57) | |
FIGO stage | |||
I+II | 11 (34) | 21 (66) | 0.054 |
III+IV | 8 (67) | 4 (33) | |
Tumour size | |||
<4 cm | 6 (32) | 13 (68) | 0.40 |
4–8 cm | 9 (53) | 8 (47) | |
⩾8 cm | 4 (50) | 4 (50) | |
Tumour localisation | |||
Upper third | 13 (54) | 11 (46) | 0.14 |
Lower third | 2 (18) | 9 (82) | |
All other locations | 4 (44) | 5 (56) | |
Growth pattern ( n =39) | |||
Exophytic | 5 (31) | 11 (69) | 0.11 |
Ulcerating | 12 (63) | 7 (37) | |
Endophytic | 1 (25) | 3 (75) | |
Local metastasis | |||
Yes | 2 (50) | 2 (50) | 1.00 |
No | 17 (43) | 23 (57) | |
Regional metastasis | |||
Yes | 1 (50) | 1 (50) | 1.00 |
No | 18 (43) | 24 (57) | |
Distant metastasis | |||
Yes | 1 (50) | 1 (50) | 1.00 |
No | 18 (43) | 24 (57) | |
Short- vs long-term survival | |||
⩽2 years | 13 (52) | 12 (48) | 0.18 |
⩾8 years | 6 (32) | 13 (68) | |
Relapse | |||
Yes | 3 (25) | 9 (75) | 0.18 |
No | 16 (50) | 16 (50) | |
