Table 7 Correlation between clinical characteristics, human papillomavirus (HPV), and survival

From: Human papillomavirus, p16INK4A, and Ki-67 in relation to clinicopathological variables and survival in primary carcinoma of the vagina

 

Survival

 
 

Short term, 2 years N (%)

Long term, 8 years N (%)

P -value

Histopathological grade

Well

7 (70)

3 (30)

0.072

Moderate

23 (68)

11 (32)

 

Poor

9 (39)

14 (61)

 

Tumour size

<4 cm

5 (17)

24 (83)

<0.001

4–8 cm

22 (81)

5 (19)

 

>8 cm

12 (100)

0 (0)

 

FIGO stage

I–II

23 (49)

24 (51)

0.036

III–IV

16 (76)

5 (24)

 

Local metastasis (tumour growth in septum rectovaginale)

Yes

6 (100)

0 (0)

0.030

No

33 (53)

29 (47)

 

Regional metastasis (inguinal node metastasis)

Yes

2 (50)

2 (50)

1.00

No

37 (58)

27 (42)

 

Distant metastasis

Yes

3 (60)

2 (40)

1.00

No

36 (57)

27 (43)

 

HPV status

Positive

13 (68)

6 (32)

0.18

Negative

12 (48)

13 (52)

 
  1. Abbreviation: FIGO=International Federation of Gynecology and Obstetrics.