Table 2 Excess HRs and 95% CI obtained from a Royston–Parmar relative survival model, modelling the risk of a cardiovascular late event for long-term survivors of cancer diagnosed between 1991 and 2006 aged 0–14 and 15–29 years inclusive
From: Cardiovascular sequelae in long-term survivors of young peoples’ cancer: a linked cohort study
95% CI | ||||
---|---|---|---|---|
Variable | HR | Lower | Upper | P -value |
Sex | ||||
Male | 1 | |||
Female | 1.43 | 0.76 | 2.68 | 0.265 |
Age at diagnosis | ||||
0–14 | 1 | |||
15–29 | 1.35 | 0.67 | 2.71 | 0.391 |
Year of diagnosis | ||||
1991–2006 | 1.01 | 0.89 | 1.14 | 0.887 |
Diagnostic group | ||||
Other solid tumours | 1 | |||
Leukaemia | 1.97 | 0.81 | 4.76 | 0.132 |
Lymphoma | 1.49 | 0.60 | 3.68 | 0.389 |
CNS tumours | 1.55 | 0.56 | 4.28 | 0.394 |
Treatment group | ||||
Sx alone/No treatment recorded | 1 | |||
Cx (+/− Sx) | 1.23 | 0.58 | 2.63 | 0.592 |
Rt (+/− Sx) | 0.39 | 0.04 | 3.66 | 0.407 |
Cx+RT (+/− Sx) | 0.92 | 0.34 | 2.54 | 0.880 |
Deprivation a | ||||
Most deprived (5) | 1 | |||
4 | 0.58 | 0.23 | 1.47 | 0.253 |
3 | 0.81 | 0.33 | 1.97 | 0.645 |
2 | 1.07 | 0.46 | 2.47 | 0.882 |
Least deprived (1) | 0.35 | 0.05 | 2.31 | 0.274 |