Figure 1

Representative images of BAP1 protein expression in primary tumours (A–C) and metastatic liver lesions (D and E) from patients with UM ( × 10 magnification). Insets show nBAP1 at × 40 magnification. Images A, B and D show strong nBAP1 protein expression in 100% of the tumour cells together with weak (A) or moderate cytoplasmic staining (B and D). Images C and E show no detectable nBAP1 protein. Image F shows nBAP1 protein expression in internal positive control pancreatic tissue.