Table 1 Association of nBAP1 status with clinical, pathological and genetic risk factors in UM
Variable | nBAP1 absent | nBAP1 present | P-value |
|---|---|---|---|
Age at PM (years) | |||
Mean | 65.4 | 55.2 | 0.002 |
Median | 65.0 | 57.0 | |
Range | 38.0–89.0 | 21.0–79.0 | |
Gender | |||
Female | 22 (50%) | 22 (50%) | 0.747 |
Male | 13 (54%) | 11 (46%) | |
LBD (mm) | |||
Mean | 16.9 | 16.0 | 0.151 |
Median | 17.5 | 15.9 | |
Range | 10.8–21.1 | 12.2–21.5 | |
UH (mm) | |||
Mean | 9.6 | 8.6 | 0.157 |
Median | 9.7 | 9.0 | |
Range | 3.4–15.7 | 2.4–14.0 | |
Ciliary body involvement | |||
Yes | 17 (81%) | 4 (19%) | 0.001 |
No | 18 (38%) | 29 (62%) | |
Epithelioid cells present | |||
Yes | 29 (62%) | 18 (32%) | 0.011 |
No | 6 (29%) | 15 (71%) | |
Closed loops present | |||
Yes | 27 (69%) | 12 (31%) | 0.001 |
No | 8 (28%) | 21 (72%) | |
Mitotic count per 40 HPF | |||
Mean | 8.3 | 6.7 | 0.235 |
Median | 7.0 | 5.0 | |
Range | 1.0–23.0 | 1.0–16.0 | |
Monosomy 3 | |||
Yes | 25 (66%) | 13 (34%) | 0.001 |
No | 8 (29%) | 20 (71%) | |
Not available | 2 (100%) | 0 | |
