Figure 3
From: Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100
Manhattan plot (left) and quantile-quantile plot (right) of genome-wide association results in E5103 under different models of hypertension. X-axis indicates the chromosomal position of each SNP analysed; Y-axis denotes magnitude of the evidence for association, shown as –log10(P-value). (A). Binary model for systolic blood pressure >160 mm Hg. (B). Cumulative dose model for the systolic blood pressure >160 mm Hg.
