Figure 4

Association results in the SVC2 region for models of hypertension defined as systolic blood pressure>160 mm Hg. Results for all genotyped and imputed SNPs that passed quality-control parameters are shown. X-axis denotes position of the SNP in the region on chromosome 5; Y-axis denotes magnitude of the evidence for association, shown as −log₁₀(P-value). The most significantly associated SNP is denoted with a purple diamond. The extent of linkage disequilibrium (as measured by r²) between each SNP and the most significantly associated SNP is indicated by the colour scale at top left. Larger values of r² indicate greater linkage disequilibrium with the most significant SNP. (A) Binary model. (B) Cumulative dose model.