Table 3 Probability of PDAC based on a combination of significant biomarkers

From: Urinary TIMP-1 and MMP-2 levels detect the presence of pancreatic malignancies

uMMP-2 (1.1 ngml–1)

uTIMP-1 (0.9 ngml–1)

Probability of PDAC

95% CI

No

No

8%

3–18%

Yes

No

35%

13–60%

No

Yes

50%

32–67%

Yes

Yes

85%

72–93%

  1. Abbreviations: CI=confidence interval; PDAC=pancreatic ductal adenocarcinoma; uMMP-2=urinary matrix metalloprotease-2; uTIMP-1= urinary tissue inhibitor of metalloprotease-1.